Risk prediction
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Stratifying early-onset emotional disorders: using genetics to assess persistence in young people of European and South Asian ancestry
Open Access paper from the JCPP – ‘We examined whether psychiatric polygenic scores (PGS) could help inform stratification efforts to predict those at higher risk of recurrence’. Charlotte A. Dennison et al.
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The influence of loss to follow-up in autism screening research: Taking stock and moving forward
Open Access paper from the JCPP – ‘How best to improve the early detection of autism spectrum disorder (ASD) is the subject of significant controversy. Some argue that universal ASD screeners are highly accurate, whereas others argue that evidence for this claim is insufficient. Relatedly, there is no clear consensus as to the optimal role of screening for making referral decisions for evaluation and treatment.’ R. Christopher Sheldrick et al.
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Children’s cognitive performance and suicide risk through middle adulthood
Paper from the JCPP – ‘Longitudinal studies show that lower cognitive performance in adolescence and early adulthood is associated with higher risk of suicide death throughout adulthood. However, it is unclear whether this cognitive vulnerability originates earlier in childhood since studies conducted in children are scarce and have inconsistent results.’ Pablo Vidal-Ribas (pic) et al.
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The importance and challenges of improving early identification of language abilities: a commentary on Gasparini et al. (2023)
Open Access paper from the JCPP – ‘Finding early predictors of later language skills and difficulties is fraught with challenges because of the wide developmental variation in language. Gasparini et al. (Journal of Child Psychology and Psychiatry, 2023) aimed to address this issue by applying machine learning methods to parent reports taken from a large longitudinal database (Early Language in Victoria Study). This commentary highlights the advantages and challenges of identifying early predictors of language in this way, and discusses future directions that can build on this important contribution.’ Nicola Botting (pic) and Helen Spicer-Cain
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Family environment and polygenic risk in the bipolar high-risk context
Open Access paper from JCPP Advances – ‘We tested the association of offspring-perceived family environment in interaction with bipolar disorder-polygenic risk on liability for bipolar disorder in offspring at high or low familial risk for bipolar disorder. We used a novel stepwise approach for latent class modeling with predictors and distal outcomes.’ Emma K. Stapp (pic) et al.
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Association between depression diagnosis and educational attainment trajectories: an historical cohort study using linked data
Open Access paper from the JCPP – To understand the association between clinical depression and course of attainment, we aimed to investigate the attainment trajectories that are generally observed among a community sample of pupils, and test the hypothesis that depression diagnosis is associated with membership of lower or declining attainment trajectories. Alice Wickersham (pic) et al.
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Research Review: A systematic review and meta-analysis of infant and toddler temperament as predictors of childhood attention-deficit/hyperactivity disorder
Paper from the JCPP – “This meta-analysis examined the associations between these early temperamental factors and later symptoms and diagnosis of ADHD and mapped early temperament constructs onto the three ADHD symptom dimensions.” Heather M. Joseph et al.
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Using machine-learning methods to identify early-life predictors of 11-year language outcome
Open Access paper from the JCPP – “This study aims to identify a parsimonious set of preschool indicators that predict language outcomes in late childhood, using data from the population-based Early Language in Victoria Study (n = 839)”. Loretta Gasparini et al.
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Prospective prediction of developing internalizing disorders in ADHD
Open Access paper from the JCPP – “Clinical course in attention-deficit/hyperactivity disorder (ADHD) is highly heterogeneous with respect to both core symptoms and associated features and impairment”. Sarah L. Karalunas (pic) et al.
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Research Review: The next 10 years of behavioural genomic research
Open Access paper from JCPP Advances – “Although the fallout has not yet settled, the goal of this paper is to predict the next 10 years of research in what could be called behavioural genomics”. Robert Plomin (pic)
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