The interaction between polygenic risk and environmental influences: A direct test of the 3P model of insomnia in adolescents

Featured ACAMH Papers

Bringing you some selected Open Access journal papers from our portfolio; The Journal of Child Psychology and Psychiatry (JCPP), Child and Adolescent Mental Health journal (CAMH), and JCPP Advances.

Posted on 4 October 2023

Tags: Family factors, Gender and gender identity… Show all

Topics: Family factors, Gender and gender identity, Gene-environment interaction, Insomnia, Stress
Populations: Adolescents
Publication Types: Blog, Journal article

Hide

‘The interaction between polygenic risk and environmental influences: A direct test of the 3P model of insomnia in adolescents’

Open Access paper from the JCPP

Stress is a universal phenomenon and one of the most common precipitants of insomnia. However, not everyone develops insomnia after experiencing a stressful life event. This study aims to test aspects of Spielman’s ‘3P model of insomnia’ (during adolescence) by exploring the extent to which: (a) insomnia symptoms are predicted by polygenic scores (PGS); (b) life events predict insomnia symptoms; (c) the interaction between PGS and life events contribute to the prediction of insomnia symptoms; (d) gene–environment interaction effects remain after controlling for sex.

Authors: Juan J. Madrid-Valero, Nicola L. Barclay, Alice M. Gregory

First published: 04 October 2024

https://doi.org/10.1111/jcpp.13895

Read the full paper

ACAMH members should follow this link: