Schizophrenia
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DNA Methylation, Lateral Ventricular Volume, and Psychiatric Risk for Schizophrenia
In this Papers Podcast, Dr. Charlotte Cecil and Dr. Mannan Luo discusses their co-authored JCPP paper ‘DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study’.
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Early manifestations of genetic liability for ADHD, autism and schizophrenia at ages 18 and 24 months
Open Access paper from JCPP Advances – “Given that ADHD, autism and schizophrenia are all highly heritable, we tested the hypothesis that in the general population, measures of toddler language development, motor development and temperament are associated with genetic liability to ADHD, autism and/or schizophrenia”. Lucy Riglin (pic) et al.
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Progressive cortical thinning might identify children at risk of developing psychotic spectrum symptoms
Offspring of patients with schizophrenia or bipolar disorder have an increased risk of developing these conditions. However, our capacity to predict the long-term outcomes of these at-risk individuals is limited. Now, researchers have investigated whether longitudinal changes in brain structure differ in individuals at high familial risk who develop psychotic spectrum symptoms, compared to those who do not and to low-risk controls.
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Can we prevent psychosis in high-risk adolescents?
Over the past two decades we’ve seen growing efforts to prevent psychosis developing in people with subtle signs and symptoms of the disorder, termed ‘Clinical High-Risk State for Psychosis’ (CHR-P).
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