Genetics
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Self-control and grit are associated with school performance mainly because of shared genetic effects
Open Access paper from JCPP Advances – ‘By combining the classical twin design with regression analysis, we investigated the role of two non-cognitive factors, self-control and grit, in the prediction of school performance. We did so at the phenotypic, genetic, and environmental level’. Sofieke T. Kevenaar et al.
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Methodological Review: Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties
Open Access paper from JCPP Advances – ‘This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study.’ Celestine Lockhart et al.
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Family environment and polygenic risk in the bipolar high-risk context
Open Access paper from JCPP Advances – ‘We tested the association of offspring-perceived family environment in interaction with bipolar disorder-polygenic risk on liability for bipolar disorder in offspring at high or low familial risk for bipolar disorder. We used a novel stepwise approach for latent class modeling with predictors and distal outcomes.’ Emma K. Stapp (pic) et al.
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Joint polygenic and environmental risks for childhood attention-deficit/hyperactivity disorder (ADHD) and ADHD symptom dimensions
Open Access paper from JCPP Advances – ‘Two independent data sets were used to examine additive (G + E) and interactive (GxE) effects of selected polygenic risk scores (PRS) and environmental factors in a cross-sectional design.’ Michael A. Mooney, Peter Ryabinin, et al.
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Genome-wide DNA methylation analysis of aggressive behaviour: a longitudinal population-based study
Open Access paper from the JCPP – ‘We examined the association between aggressive behaviour, as measured by Life History of Aggression (LHA) total score and DNAm levels both assessed at age 25.’ Ehsan Pishva (pic) et al.
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Autism spectrum disorder and brain volume link through a set of mTOR-related genes
Open Access paper from the JCPP – ‘Here we investigated whether variants in mTOR-related genes are also associated with ASD and if they constitute a genetic link between large brains and ASD.’ Martina Arenella et al.
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Commentary: Something old, something new – can adding genomic data to family studies advance our understanding of the impact of nature and nurture on mental health? Commentary on McAdams et al. (2023)
Open Access paper from the JCPP – ‘In their annual research review, McAdams, Cheesman, and Ahmadzadeh (2023) provide a thorough overview of how the use of novel genetically informative approaches can increase our knowledge about the intergenerational transmission of psychopathology. Here we highlight what we see as the three main takeaways of McAdams et al.’s review and reflect on future directions.’ Jasmin Wertz and Stephanie J. Lewis
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Annual Research Review: Prenatal opioid exposure – a two-generation approach to conceptualizing neurodevelopmental outcomes
Paper from the JCPP Special Issue: Annual Research Review 2023 – ‘Opioid use during pregnancy impacts the health and well-being of two generations: the pregnant person and the child. The factors that increase risk for opioid use in the adult, as well as those that perpetuate risk for the caregiver and child, oftentimes replicate across generations and may be more likely to affect child neurodevelopment than the opioid exposure itself. In this article, we review the prenatal opioid exposure literature with the perspective that this is not a singular event but an intergenerational cascade of events.’ Elisabeth Conradt (pic) et al.
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Methodological Review: Why we need families in genomic research on developmental psychopathology
Open Access from JCPP Advances – ‘The goal of this paper is to review how combining DNA-based genomic research with family-based quantitative genetics helps to address key issues in genomics and push knowledge further.’ Rosa Cheesman (pic) et al.
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Factors related to retention in a longitudinal study of infants at familial risk for autism
Open Access paper from JCPP Advances – ‘We examined multiple child- and family-level factors potentially associated with retention in a longitudinal study of younger siblings of children with autism spectrum disorder or typical development.’ Sally Ozonoff et al.
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