Brain
-
Progressive cortical thinning might identify children at risk of developing psychotic spectrum symptoms
Offspring of patients with schizophrenia or bipolar disorder have an increased risk of developing these conditions. However, our capacity to predict the long-term outcomes of these at-risk individuals is limited. Now, researchers have investigated whether longitudinal changes in brain structure differ in individuals at high familial risk who develop psychotic spectrum symptoms, compared to those who do not and to low-risk controls.
Read more -
Emotional abuse during childhood is linked with differences in brain structure
Delia Gheorghe and colleagues at the University of Oxford have harnessed data from the UK Biobank to delineate the relationship between adverse experiences and brain structure. The researchers accessed brain imaging data together with retrospective reports of childhood adversity and adulthood partner abuse from more than 6,000 adults (mean age, 62.1 years).
Read more -
Mothers’ prenatal BMI is linked with foetal brain connectivity
New data suggest that a high maternal prenatal body mass index (BMI) is associated with differences in functional connectivity in the foetal brain that might confer a risk of mental health and cognitive problems in childhood.
Read more -
Do brain function abnormalities lead to substance use, or vice versa?
New research has, for the first time, investigated the direction of links between brain function and substance use throughout adolescence. Jungmeen Kim-Spoon and colleagues studied 167 adolescents who were assessed annually for four years from 13-14 years old.
Read more -
Does late-onset ADHD share the same neurocognitive markers as childhood-onset ADHD?
Researchers in the Netherlands have published their findings from a 6-year prospective, longitudinal study that aimed to identify neurocognitive markers of late-onset attention-deficit/hyperactivity disorder (ADHD).
Read more -
Paediatric anxiety disorders confer a considerable public health burden
Anxiety disorders usually begin in childhood or adolescence and are the most common mental health condition across the life span.1,2 Consequently, intense research efforts are focused on delineating the underlying mechanisms of paediatric anxiety so that we can better identify those at risk and intervene early.
Read more -
Is brain circuitry linked with early symptoms of autism spectrum disorder?
Researchers in San Diego, USA, have studied the relationship between brain network connectivity and emerging autism spectrum disorder (ASD) symptoms in toddlers aged 17-45 months with (n=24) or without (n=23) ASD.
Read more -
Young people’s ‘neural fingerprints’ might permit a precision-medicine approach to depression
Precision medicine has been discussed in medical research since the late 1990’s. Only recently, however, has this concept aroused interest and inspired relevant research in psychiatry, particularly in adolescents.
Read more -
‘Resilience – a complexity science approach’ Professor Anne-Laura Van Harmelen – ‘In Conversation’
Professor Anne-Laura Van Harmelen talks about her new appointment of Professor of Brain Safety and Resilience, the work of Risk and Resilience Group, and its work on HOPES project and RAISE Study.
Read more -
What mechanisms underlie reduced social attention in people with ASD?
A key predictor of an autism spectrum disorder (ASD) diagnosis is attenuated attention to social stimuli.1 Thus far, the reasons underlying this abnormality are unknown: some have hypothesized reduced social motivation2 while others have suggested aberrant oculomotor function in affected individuals.3
Read more