Brain
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Annual Research Review: Neuroimmune network model of depression: a developmental perspective
Open Access paper from the JCPP – ‘We have three goals for the present paper. First, we extend neuroimmune network models of mental and physical health to generate a developmental framework of risk for the onset of depression during adolescence. Second, we examine how a neuroimmune network perspective can help explain the high rates of comorbidity between depression and other psychiatric disorders across development, and multimorbidity between depression and stress-related medical illnesses. Finally, we consider how identifying neuroimmune pathways to depression can facilitate a ‘next generation’ of behavioral and biological interventions that target neuroimmune signaling to treat, and ideally prevent, depression in youth and adolescents.’ Robin Nusslock (pic) et al.
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A network approach to the investigation of childhood irritability: probing frustration using social stimuli
Paper from the JCPP – ‘Currently, there is inconsistency in the identification of neural circuits that underlie irritability in children, especially in social contexts. This study aimed to address this gap by utilizing a functional magnetic resonance imaging (fMRI) paradigm to investigate pediatric anger/frustration using social stimuli.’ Khalil I. Thompson et al.
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DNA Methylation, Lateral Ventricular Volume, and Psychiatric Risk for Schizophrenia
In this Papers Podcast, Dr. Charlotte Cecil and Dr. Mannan Luo discusses their co-authored JCPP paper ‘DNA methylation at birth and lateral ventricular volume in childhood: a neuroimaging epigenetics study’.
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Interplay of early negative life events, development of orbitofrontal cortical thickness and depression in young adulthood
Open Access paper from JCPP Advances – ‘Using a complete longitudinal design with four time points, we examined whether NLE during childhood and early adolescence predict depressive symptoms in young adulthood through accelerated OFC thinning across adolescence.’ Lea L. Backhausen (pic) and Jonas Granzow et al.
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Oxytocin Administration, Neural Sensitivity, and Autism
In this Papers Podcast, Dr. Matthijs Moerkerke discusses his JCPP paper ‘Can repeated intranasal oxytocin administration affect reduced neural sensitivity towards expressive faces in autism? A randomized controlled trial’. Matthijs is the first author of the paper.
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JCPP Editorial: Volume 64, Issue 10, October 2023
Editorial: “Paradigm ‘flipping’ to reinvigorate translational science: Outlining a neurodevelopmental science framework from a ‘neurodiversity’ perspective” by Edmund J. S. Sonuga-Barke
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Practitioner Review: Neurobiological consequences of childhood maltreatment – clinical and therapeutic implications for practitioners
Paper from the JCPP – ‘In this report, we explore key validated alterations in brain structure, function, and connectivity associated with exposure to childhood maltreatment as potential mechanisms behind their patients’ clinical presentations.’ Jacqueline A. Samson (pic) et al.
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Categorical versus Dimensional Structure of Autism
In this Papers Podcast, Dr. Tom Frazier discusses his JCPP Advances paper ‘Categorical versus dimensional structure of autism spectrum disorder: A multi-method investigation’. Tom is the first author of the paper.
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Report from a randomized control trial: improved alignment between circadian biology and sleep–wake behavior as a mechanism of depression symptom improvement in evening-type adolescents with depressive symptoms
Open Access paper from the JCPP – ‘These results provide novel evidence for improved alignment between circadian biology and sleep–wake behavior as a specific mechanism of depression improvement, provide key clues into the complex relationship between sleep and depression, and have significant clinical implications for adolescents with depression.’ Lauren D. Asarnow (pic) et al.
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Transdiagnostic Profiles of Behaviour and Communication: Academic and Socioemotional Functioning and Neural White Matter Organisation
In this Papers Podcast, Dr. Silvana Mareva discusses her JCPP paper ‘Transdiagnostic profiles of behaviour and communication relate to academic and socioemotional functioning and neural white matter organisation’. Silvana is the first author of the paper.
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